UNIT X: TRANSPLANTATION


A. Cardiac Transplantation



Contents:

  1. Indications for cardiac transplantation
    1. Patient evaluation
    2. Patient selection
    3. Informed consent

  2. Immunosuppressive therapy in cardiac transplantation
    1. Evaluation of therapy
    2. Drugs
    3. Complications

  3. Technique of cardiac transplantation
    1. Orthotopic
    2. Heterotopic

  4. Donor preparation and organ harvest
    1. Brain death, legal and family-related issues
    2. Donor evaluation
    3. Methods of organ procurement and preservation

  5. Cardiac rejection
    1. Signs and symptoms
    2. Endomyocardial biopsy
    3. Histologic evaluation
    4. Management
    5. Mechanical support and re-transplantation

  6. Immunosuppressive therapy
    1. Immunosuppressive drugs and their side effects
    2. Polyclonal and monoclonal antibody therapy and side effects
    3. Complications

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